Biomarkers of over-immunosuppression.
نویسندگان
چکیده
An important goal in transplantation is to tailor immuno suppression to the individual needs of the patient, avoiding both rejection and overimmunosuppression. Opportunistic infections and malignancies remain a significant cause of death after transplantation and are obvious consequences of overimmunosuppression. Currently, monitoring of immunosuppression is conducted mainly on the basis of pharmacokinetic characteristics, which do not necessarily predict clinical outcome in the individual. This review focuses on the potential of using biomarkers as a monitoring tool to prevent overimmunosuppression after transplantation.
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ورودعنوان ژورنال:
- Clinical pharmacology and therapeutics
دوره 90 2 شماره
صفحات -
تاریخ انتشار 2011